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2022
Tuning the rate of aggregation of hIAPP into amyloid using smallmolecule modulators of assembly
Y Xu, R Maya-Martinez, N Guthertz, GR Heath, IW Manfield, A Breeze, F Sobott, R Foster, SE Radford.
Nature Communications (2022 In press)
2021
Correlation of membrane protein conformational and functional dynamics
Sanganna Gari RR, Montalvo‐Acosta JJ, Heath GR, Jiang Y, Gao X, Nimigea CM, Chipot C, Scheuring S. Nature Communications. 12, 4363 (2021).
Localization Atomic Force Microscopy
Heath GR, Kots E, Robertson JL, Lansky S, G Khelashvili, Weinstein H & Scheuring S.
Nature, 594, 7863 (2021).
The structure of a native orthobunyavirus ribonucleoprotein reveals a key role for viral RNA in maintaining its helical architecture
Hopkins FR, Álvarez-Rodríguez B, Heath GR, Panayi K, Hover S, Edwards TA, Barr JN and Fontana J. bioRxiv, (2021).
Structural dynamics of channels and transporters by high-speed atomic force microscopy.
Heath GR, Lin YC, Matin TR and Scheuring S. Ion Channels: Channel Biochemistry, Reconstitution, and Function. 127, (2021).
2020
Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly
Gallardo R, Iadanza MG, Xu Y, Heath GR, Foster R, Radford SE & Ranson NA. Nature Structure and Molecular Biology, Cover article, 27 (11), (2020).
Millisecond dynamics of an unlabeled amino acid transporter
Matin TR, Heath GR, Huysmans, GH, Boudker O & Scheuring S. Nature Communications 11(1) 1-11 (2020).
Out-of-Plane Nanoscale Reorganization of Lipid Molecules and Nanoparticles Revealed by Plasmonic Spectroscopy
Cheetham MR, Griffiths J, Nijs BD, Heath GR, Evans SD, Baumberg JJ & Chikkaraddy R. J Phys. Chem. Lett. 11, 8, (2020).
2019
Advances in high-speed atomic force microscopy (HS-AFM) reveal dynamics of transmembrane channels and transporters
Heath GR & Scheuring S. Current Opinions in Structural Biology 57, (2019).
2018
High-Speed AFM Height Spectroscopy (HS-AFM-HS): μs dynamics of unlabeled biomolecules
Heath GR & Scheuring S. Nature Communications, 9, 1, (2018)
Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes
Heath GR, Harrison P. L, Strong P. N, Evans S. D, Miller K. Soft Matter, 14, 29, (2018)
2017
Multilayered Lipid Membrane Stacks for Biocatalysis Using Membrane Enzymes
Heath GR, Li M, Rong H, Radu V, Frielingsdorf S et al. Advanced Functional Materials, Cover article, 27, 17, (2017).
2016
Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom
Harrison PL, Heath GR, Johnson BRG, Abdel-Rahman MA, Strong PN et. al. BBA Biomembranes, 1858, 11, (2016).
Highly Fluorescent Ribonuclease-A-Encapsulated Lead Sulfide Quantum Dots for Ultrasensitive fluorescence in Vivo Imaging in the Second Near-Infrared Window
Kong Y, Chen J, Fang H, Heath GR, Wo Y, Wang W, et al. Chem. Mater. 28, 9, (2016).
Layer-by-layer assembly of supported lipid bilayer poly-l-lysine multilayers
Heath GR, Li M, Polignano IL, Richens JL, Catucci G et al. Biomacromolecules, 17, 1, (2016).
2015
New poly(amino acid methacrylate) brush supports the formation of well-defined lipid membranes
Blakeston AC, Alswieleh AM, Heath GR, Roth JS, Bao P, Cheng N, et al. Langmuir, 31, 12, (2015).
2014
Diffusion in low-dimensional lipid membranes
Heath GR, Roth J, Connell SD, Evans SD. Nano Letters, 14, 10, (2014).
Watching individual molecules flex within lipid membranes using SERS
Taylor RW, Benz F, Sigle DO, Bowman RW, Bao P, Roth JS, Heath GR, et. al. Scientific Reports, 4, (2014).
Self-assembly of actin scaffolds on lipid microbubbles
Heath GR, Abou-Saleh RH, Peyman SA, Johnson BRG, Connell SD, Evans SD. Soft Matter, Cover article 10, 5, (2014).
2013
Actin assembly at model-supported lipid bilayers
Heath GR, Johnson BRG, Olmsted PD, Connell SD, Evans SD. Biophys Journal, 105, 10, (2013).
Near-infrared fluorescent ribonuclease-A-encapsulated gold nanoclusters: Preparation, characterization, cancer targeting and imaging
Kong Y, Chen J, Gao F, Brydson R, Johnson B, Heath G, et al. Nanoscale, 5, 3, (2013).
2012
Critical point fluctuations in supported lipid membranes
Connell SD, Heath G, Olmsted PD, Kisil A. Faraday Discussions, 161, (2012).